It has long been noticed geographical or national differences in prostate cancer susceptibility. These variations were mostly attributed to the specificity of the diet and culinary preferences of different cultures. And this, in turn, suggests that some foods or ingredients of food may have chemoprotective properties against cancer cells. Lycopene, selenium, vitamins C, D, E, and K, green tea, silymarin, pomegranate, and Resveratrol are well-known dietary components that attracted considerable attention from scientists in terms of their anticancer potential. Here I’ll focus on vitamin K2 and its varieties as the natural food components capable of stopping the development of prostate cancer or slowing down its progression.